Publications

Crystal structure of the nucleosome core particle at 2.8 Å resolution

Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences

The UK Biobank resource with deep phenotyping and genomic data

Abstract The UK Biobank project is a prospective cohort study with deep genetic and phenotypic data collected on approximately 500,000 individuals from across the United Kingdom...

Dating of the human-ape splitting by a molecular clock of mitochondrial DNA

The Cancer Genome Atlas Pan-Cancer analysis project

ColabFold: making protein folding accessible to all

Abstract ColabFold offers accelerated prediction of protein structures and complexes by combining the fast homology search of MMseqs2 with AlphaFold2 or RoseTTAFold. ColabFold’s...

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

The language of covalent histone modifications

ape 5.0: an environment for modern phylogenetics and evolutionary analyses in R

Abstract Summary After more than fifteen years of existence, the R package ape has continuously grown its contents, and has been used by a growing community of users. The releas...

Comprehensive molecular characterization of human colon and rectal cancer

Dexamethasone in Hospitalized Patients with Covid-19.

BACKGROUND: Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progres...

The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets

Abstract Cellular life depends on a complex web of functional associations between biomolecules. Among these associations, protein–protein interactions are particularly importan...