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TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

Sanjeev Mariathasan , Shannon J. Turley , Dorothee Nickles +39 more

2018 Nature 5078 citations

The GTEx Consortium atlas of genetic regulatory effects across human tissues

François Aguet , Shankara Anand , Kristin Ardlie +97 more

The Genotype-Tissue Expression (GTEx) project dissects how genetic variation affects gene expression and splicing.

2020 Science 4992 citations

Clinical and immunological features of severe and moderate coronavirus disease 2019

Guang Chen , Di Wu , Wei Guo +17 more

BACKGROUNDSince December 2019, an outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, and is...

2020 Journal of Clinical Investigation 4983 citations

Dissecting racial bias in an algorithm used to manage the health of populations

Ziad Obermeyer , Brian W. Powers , Christine Vogeli +1 more

Racial bias in health algorithms The U.S. health care system uses commercial algorithms to guide health decisions. Obermeyer et al. find evidence of racial bias in one widely us...

2019 Science 4979 citations

Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study

Hana Štorkánová , Sabína Oreská , Maja Špiritović +9 more

2021 Scientific Reports 4939 citations

Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China

Chuan Qin , Luo‐Qi Zhou , Ziwei Hu +8 more

Abstract Background In December 2019, coronavirus 2019 (COVID-19) emerged in Wuhan and rapidly spread throughout China. Methods Demographic and clinical data of all confirmed ca...

2020 Clinical Infectious Diseases 4935 citations