Donanemab in Early Symptomatic Alzheimer Disease
Importance There are limited efficacious treatments for Alzheimer disease. Objective To assess efficacy and adverse events of donanemab, an antibody designed to clear brain amyl...
Publications
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647 publications
Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
Exchange of extracellular cystine for intracellular glutamate by the antiporter system x c − is implicated in numerous pathologies. Pharmacological agents that inhibit system x ...
Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes
In December 2019, a novel coronavirus (2019-nCoV) caused an outbreak in Wuhan, China, and soon spread to other parts of the world. It was believed that 2019-nCoV was transmitted...
COVID-19 pneumonia: different respiratory treatments for different phenotypes?
The Surviving Sepsis Campaign panel recently recom-mended that “mechanically ventilated patients with COVID-19 should be managed similarly to other patients with acute respirato...
Development and clinical application of a rapid IgM‐IgG combined antibody test for SARS‐CoV‐2 infection diagnosis
Abstract The outbreak of the novel coronavirus disease (COVID‐19) quickly spread all over China and to more than 20 other countries. Although the virus (severe acute respiratory...
Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study
OBJECTIVE: Since the outbreak of Coronavirus Disease 2019 (COVID-19) in December 2019, various digestive symptoms have been frequently reported in patients infected with the vir...
Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful modern pathogens. The same organism that lives as a commensal and is transmitted in both health-...
Functional exhaustion of antiviral lymphocytes in COVID-19 patients
In December 2019, a novel coronavirus was first reported in Wuhan, China. It was named by the World Health Organization as severe acute respiratory syndrome coronavirus 2 (SARS-...
Measuring climate for work group innovation: development and validation of the team climate inventory
This paper reports the development and psychometric validation of a multi-dimensional measure of facet-specific climate for innovation within groups at work: the Team Climate In...
The impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis in England, UK: a national, population-based, modelling study
Since a national lockdown was introduced across the UK in March, 2020, in response to the COVID-19 pandemic, cancer screening has been suspended, routine diagnostic work deferre...
“Pandemic fear” and COVID-19: mental health burden and strategies
‘‘Pandemic fear’’ and COVID-19: mental health burden and strategies Felipe Ornell,0000-0001-8638-5842 Jaqueline B. Schuch,0000-0001-8638-5842 Anne O. Sordi,0000-0001-8638-5842 F...
Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia
A heterologous recombinant adenovirus (rAd)-based vaccine, Gam-COVID-Vac (Sputnik V), showed a good safety profile and induced strong humoral and cellular immune responses in pa...