Hallmarks of Cancer: New Dimensions
Abstract The hallmarks of cancer conceptualization is a heuristic tool for distilling the vast complexity of cancer phenotypes and genotypes into a provisional set of underlying...
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584 publications
The MR-Base platform supports systematic causal inference across the human phenome
Results from genome-wide association studies (GWAS) can be used to infer causal relationships between phenotypes, using a strategy known as 2-sample Mendelian randomization (2SM...
A Rapid Bootstrap Algorithm for the RAxML Web Servers
Despite recent advances achieved by application of high-performance computing methods and novel algorithmic techniques to maximum likelihood (ML)-based inference programs, the m...
Homo Sacer
One of Italy's most original philosophers aims to connect the problem of pure possibility, potentiality, and power with the problem of political and social ethics in a context w...
OrthoFinder: phylogenetic orthology inference for comparative genomics
Abstract Here, we present a major advance of the OrthoFinder method. This extends OrthoFinder’s high accuracy orthogroup inference to provide phylogenetic inference of orthologs...
Honeycomb Carbon: A Review of Graphene
ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTHoneycomb Carbon: A Review of GrapheneMatthew J. Allen†, Vincent C. Tung‡, and Richard B. Kaner*†‡View Author Information Department o...
Planetary Boundaries: Exploring the Safe Operating Space for Humanity
"Anthropogenic pressures on the Earth System have reached a scale where abrupt global environmental change can no longer be excluded. We propose a new approach to global sustain...
Power-law distributions in empirical data
Power-law distributions occur in many situations of scientific interest and have significant consequences for our understanding of natural and man-made phenomena. Unfortunately,...
Anarchy, State, and Utopia
Robert Nozicka s Anarchy, State, Utopia is a powerful, philosophical challenge to the most widely held political social positions of our age ---- liberal, socialist conservat...
BEAST 2: A Software Platform for Bayesian Evolutionary Analysis
We present a new open source, extensible and flexible software platform for Bayesian evolutionary analysis called BEAST 2. This software platform is a re-design of the popular B...
Improving neural networks by preventing co-adaptation of feature detectors
When a large feedforward neural network is trained on a small training set, it typically performs poorly on held-out test data. This "overfitting" is greatly reduced by randomly...