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EuroQol - a new facility for the measurement of health-related quality of life
In the course of developing a standardised, non-disease-specific instrument for describing and valuing health states (based on the items in Table 1), the EuroQol Group (whose me...
Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review
<b><i>Background:</i></b> Cancer immunotherapy, such as anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and anti-programmed death 1 (PD-1), has...
Motivation and Personality
Perspectives on Sexuality Sex Research - an Overview Part 1. Biological Perspectives: Sexual Anatomy 1. Sexual Physiology 2. Human Reproduction 3. Birth Control 4. Abortion Part...
Prediction of Creatinine Clearance from Serum Creatinine
A formula has been developed to predict creatinine clearance (Ccr) from serum creatinine (Scr) in adult males: (see article)(15% less in females). Derivation included the relati...
Global Prevalence of Diabetes
OBJECTIVE—The goal of this study was to estimate the prevalence of diabetes and the number of people of all ages with diabetes for years 2000 and 2030. RESEARCH DESIGN AND METHO...
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO Consultation
The classification of diabetes mellitus and the tests used for its diagnosis were brought into order by the National Diabetes Data Group of the USA and the second World Health O...
Development and Testing of the OPLS All-Atom Force Field on Conformational Energetics and Properties of Organic Liquids
The parametrization and testing of the OPLS all-atom force field for organic molecules and peptides are described. Parameters for both torsional and nonbonded energetics have be...
All-Atom Empirical Potential for Molecular Modeling and Dynamics Studies of Proteins
New protein parameters are reported for the all-atom empirical energy function in the CHARMM program. The parameter evaluation was based on a self-consistent approach designed t...
<i>MolProbity</i>: all-atom structure validation for macromolecular crystallography
MolProbity is a structure-validation web service that provides broad-spectrum solidly based evaluation of model quality at both the global and local levels for both proteins and...