Measuring the Accuracy of Diagnostic Systems
Diagnostic systems of several kinds are used to distinguish between two classes of events, essentially "signals" and "noise." For them, analysis in terms of the "relative operat...
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558 publications
Statistical parametric maps in functional imaging: A general linear approach
Abstract Statistical parametric maps are spatially extended statistical processes that are used to test hypotheses about regionally specific effects in neuroimaging data. The mo...
Neutrophil Extracellular Traps Kill Bacteria
Neutrophils engulf and kill bacteria when their antimicrobial granules fuse with the phagosome. Here, we describe that, upon activation, neutrophils release granule proteins and...
A general and simple method for obtaining <i>R</i> <sup>2</sup> from generalized linear mixed‐effects models
Summary The use of both linear and generalized linear mixed‐effects models ( LMM s and GLMM s) has become popular not only in social and medical sciences, but also in biological...
<i>The Brain's Default Network</i>
Thirty years of brain imaging research has converged to define the brain's default network—a novel and only recently appreciated brain system that participates in internal modes...
A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster
An ongoing outbreak of pneumonia associated with a novel coronavirus was reported in Wuhan city, Hubei province, China. Affected patients were geographically linked with a local...
The Genotype-Tissue Expression (GTEx) project.
Genome-wide association studies have identified thousands of loci for common diseases, but, for the majority of these, the mechanisms underlying disease susceptibility remain un...
PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews
The methods and results of systematic reviews should be reported in sufficient detail to allow users to assess the trustworthiness and applicability of the review findings. The ...
Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample
The ongoing revolution in high-throughput sequencing continues to democratize the ability of small groups of investigators to map the microbial component of the biosphere. In pa...
The mutational constraint spectrum quantified from variation in 141,456 humans
Genetic variants that inactivate protein-coding genes are a powerful source of information about the phenotypic consequences of gene disruption: genes that are crucial for the f...
A Brief History of Neoliberalism
Neoliberalism--the doctrine that market exchange is an ethic in itself, capable of acting as a guide for all human action--has become dominant in both thought and practice throu...