Publications

Initial sequencing and analysis of the human genome

The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collabor...

A pneumonia outbreak associated with a new coronavirus of probable bat origin

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

MRBAYES: Bayesian inference of phylogenetic trees

Abstract Summary: The program MRBAYES performs Bayesian inference of phylogeny using a variant of Markov chain Monte Carlo. Availability: MRBAYES, including the source code, doc...

Introduction to Quantitative Genetics.

Part 1 Genetic constitution of a population: Hardy-Weinberg equilibrium. Part 2 Changes in gene frequency: migration mutation. Part 3 Small populations - changes in gene frequen...

Full-length transcriptome assembly from RNA-Seq data without a reference genome

HTSeq—a Python framework to work with high-throughput sequencing data

Abstract Motivation: A large choice of tools exists for many standard tasks in the analysis of high-throughput sequencing (HTS) data. However, once a project deviates from stand...

Detecting the number of clusters of individuals using the software <scp>structure</scp>: a simulation study

Abstract The identification of genetically homogeneous groups of individuals is a long standing issue in population genetics. A recent Bayesian algorithm implemented in the soft...

BLAST+: architecture and applications

Abstract Background Sequence similarity searching is a very important bioinformatics task. While Basic Local Alignment Search Tool (BLAST) outperforms exact methods through its ...

Introducing mothur: Open-Source, Platform-Independent, Community-Supported Software for Describing and Comparing Microbial Communities

ABSTRACT mothur aims to be a comprehensive software package that allows users to use a single piece of software to analyze community sequence data. It builds upon previous tools...

Cancer statistics, 2020

Abstract Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths that will occur in the United States and compiles the most recent data on po...