Cancer treatment and survivorship statistics, 2022
Abstract The number of cancer survivors continues to increase in the United States due to the growth and aging of the population as well as advances in early detection and treat...
Publications
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161 publications
Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma
BACKGROUND Nivolumab plus ipilimumab or nivolumab alone resulted in longer progression-free and overall survival than ipilimumab alone in a trial involving patients with advance...
An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
The mRNA-1273 vaccine induced anti-SARS-CoV-2 immune responses in all participants, and no trial-limiting safety concerns were identified. These findings support further develop...
GEOquery: a bridge between the Gene Expression Omnibus (GEO) and BioConductor
Abstract Microarray technology has become a standard molecular biology tool. Experimental data have been generated on a huge number of organisms, tissue types, treatment conditi...
Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
Clonal hematopoiesis with somatic mutations is readily detected by means of DNA sequencing, is increasingly common as people age, and is associated with increased risks of hemat...
Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
Inflammatory conditions in selected organs increase the risk of cancer. An inflammatory component is present also in the microenvironment of tumors that are not epidemiologicall...
Dietary Reference Intakes for Calcium and Vitamin D
The charge to the committee (Institute of Medicine Committee to Review Dietary Reference Intakes for Vitamin D and Calcium) was to assess current relevant data and update, as ap...
Next century challenges
Article Free Access Share on Next century challenges: scalable coordination in sensor networks Authors: Deborah Estrin USC/Information Sciences Institute, 4676 Admiralty Way, Ma...
Continuum solvation models: A new approach to the problem of solute’s charge distribution and cavity boundaries
In continuum solvation models the definition of a cavity that embeds the solute molecule leads to problems related to the portion of solute’s electronic charge lying outside its...
Nonalcoholic Fatty Liver, Steatohepatitis, and the Metabolic Syndrome
Nonalcoholic fatty liver disease (NAFLD) has been associated with the insulin–resistance syndrome, at present defined as the metabolic syndrome, whose limits were recently set. ...
Diagnosis of Alzheimer's Disease
Early and accurate diagnosis of Alzheimer's disease (AD) has a major impact on the progress of research on dementia. To address the problems involved in diagnosing AD in its ear...