Publications

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

A two-dose regimen of BNT162b2 conferred 95% protection against Covid-19 in persons 16 years of age or older. Safety over a median of 2 months was similar to that of other viral...

Tissue-based map of the human proteome

Protein expression across human tissues Sequencing the human genome gave new insights into human biology and disease. However, the ultimate goal is to understand the dynamic exp...

Minimap2: pairwise alignment for nucleotide sequences

Abstract Motivation Recent advances in sequencing technologies promise ultra-long reads of ∼100 kb in average, full-length mRNA or cDNA reads in high throughput and genomic cont...

Raman Spectrum of Graphene and Graphene Layers

Graphene is the two-dimensional building block for carbon allotropes of every other dimensionality. We show that its electronic structure is captured in its Raman spectrum that ...

Evolutionary trees from DNA sequences: A maximum likelihood approach

TBtools: An Integrative Toolkit Developed for Interactive Analyses of Big Biological Data

Mapping and quantifying mammalian transcriptomes by RNA-Seq

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

Integrating single-cell transcriptomic data across different conditions, technologies, and species

The Sequence of the Human Genome

A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp ...

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

A method and server for predicting damaging missense mutations