Fast model-based estimation of ancestry in unrelated individuals
Population stratification has long been recognized as a confounding factor in genetic association studies. Estimated ancestries, derived from multi-locus genotype data, can be u...
Publications
Explore 466 academic publications
Showing 12 of
466 publications
The Cambridge Structural Database
The Cambridge Structural Database (CSD) contains a complete record of all published organic and metal–organic small-molecule crystal structures. The database has been in operati...
Chord
A fundamental problem that confronts peer-to-peer applications is to efficiently locate the node that stores a particular data item. This paper presents Chord, a distributed loo...
The Benefits of Facebook “Friends:” Social Capital and College Students’ Use of Online Social Network Sites
This study examines the relationship between use of Facebook, a popular online social network site, and the formation and maintenance of social capital. In addition to assessing...
<i>The Brain's Default Network</i>
Thirty years of brain imaging research has converged to define the brain's default network—a novel and only recently appreciated brain system that participates in internal modes...
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
There is increasing evidence that genome-wide association (GWA) studies represent a powerful approach to the identification of genes involved in common human diseases. We descri...
‘Small Changes' to Diet and Physical Activity Behaviors for Weight Management
Obesity is associated with numerous short- and long-term health consequences. Low levels of physical activity and poor dietary habits are consistent with an increased risk of ob...
Signal Recovery From Random Measurements Via Orthogonal Matching Pursuit
This paper demonstrates theoretically and empirically that a greedy algorithm called Orthogonal Matching Pursuit (OMP) can reliably recover a signal with $m$ nonzero entries in ...
The Genotype-Tissue Expression (GTEx) project.
Genome-wide association studies have identified thousands of loci for common diseases, but, for the majority of these, the mechanisms underlying disease susceptibility remain un...
Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample
The ongoing revolution in high-throughput sequencing continues to democratize the ability of small groups of investigators to map the microbial component of the biosphere. In pa...