UniProt: the Universal Protein Knowledgebase in 2023
Abstract The aim of the UniProt Knowledgebase is to provide users with a comprehensive, high-quality and freely accessible set of protein sequences annotated with functional inf...
Publications
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1,686 publications
Correlation of Chest CT and RT-PCR Testing for Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases
Background Chest CT is used in the diagnosis of coronavirus disease 2019 (COVID-19) and is an important complement to reverse-transcription polymerase chain reaction (RT-PCR) te...
Oxidants, antioxidants, and the degenerative diseases of aging.
Metabolism, like other aspects of life, involves tradeoffs. Oxidant by-products of normal metabolism cause extensive damage to DNA, protein, and lipid. We argue that this damage...
Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data
ABSTRACT Genome‐wide association studies, which typically report regression coefficients summarizing the associations of many genetic variants with various traits, are potential...
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference
This document reflects a process whereby a group of experts and opinion leaders revisited the 1992 sepsis guidelines and found that apart from expanding the list of signs and sy...
Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes
In patients with type 2 diabetes who had or were at risk for atherosclerotic cardiovascular disease, treatment with dapagliflozin did not result in a higher or lower rate of MAC...
Likelihood Ratio Tests for Model Selection and Non-Nested Hypotheses
In this paper, we develop a classical approach to model selection. Using the Kullback-Leibler Information Criterion to measure the closeness of a model to the truth, we propose ...