Development and testing of a general amber force field
Abstract We describe here a general Amber force field (GAFF) for organic molecules. GAFF is designed to be compatible with existing Amber force fields for proteins and nucleic a...
Publications
Explore 1,004 academic publications
Showing 12 of
1,004 publications
Delving Deep into Rectifiers: Surpassing Human-Level Performance on ImageNet Classification
Rectified activation units (rectifiers) are essential for state-of-the-art neural networks. In this work, we study rectifier neural networks for image classification from two as...
New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0
PhyML is a phylogeny software based on the maximum-likelihood principle. Early PhyML versions used a fast algorithm performing nearest neighbor interchanges to improve a reasona...
Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the n...
The magical number seven, plus or minus two: Some limits on our capacity for processing information.
First, the span of absolute judgment and the span of immediate memory impose severe limitations on the amount of information that we are able to receive, process, and remember. ...
The magical number seven, plus or minus two: Some limits on our capacity for processing information.
First, the span of absolute judgment and the span of immediate memory impose severe limitations on the amount of information that we are able to receive, process, and remember. ...
Towards Learning Terminological Concept Systems from Multilingual Natural Language Text
Terminological Concept Systems (TCS) provide a means of organizing, structuring and representing domain-specific multilingual information and are important to ensure terminologi...
Bootstrap Methods: Another Look at the Jackknife
We discuss the following problem: given a random sample $\\mathbf{X} = (X_1, X_2, \\cdots, X_n)$ from an unknown probability distribution $F$, estimate the sampling distribution...
Can Quantum-Mechanical Description of Physical Reality Be Considered Complete?
In a complete theory there is an element corresponding to each element of reality. A sufficient condition for the reality of a physical quantity is the possibility of predicting...
Robust uncertainty principles: exact signal reconstruction from highly incomplete frequency information
This paper considers the model problem of reconstructing an object from incomplete frequency samples. Consider a discrete-time signal f ∈ C N and a randomly chosen set of freque...
Parallel Distributed Processing
What makes people smarter than computers? These volumes by a pioneering neurocomputing group suggest that the answer lies in the massively parallel architecture of the human min...
Tissue-based map of the human proteome
Protein expression across human tissues Sequencing the human genome gave new insights into human biology and disease. However, the ultimate goal is to understand the dynamic exp...