Publications

Cancer: Principles and Practice of Oncology.

Part I: Molecular Biology of Cancer Molecular Methods in Oncology Section 1. Amplification Techniques Section 2. RNA Interference Section 3. cDNA arrays Section 4. Tissue arrays...

Adjusting batch effects in microarray expression data using empirical Bayes methods

Non-biological experimental variation or "batch effects" are commonly observed across multiple batches of microarray experiments, often rendering the task of combining data from...

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

MEGAHIT: an ultra-fast single-node solution for large and complex metagenomics assembly via succinct <i>de Bruijn</i> graph

Abstract Summary: MEGAHIT is a NGS de novo assembler for assembling large and complex metagenomics data in a time- and cost-efficient manner. It finished assembling a soil metag...

The language of covalent histone modifications

ape 5.0: an environment for modern phylogenetics and evolutionary analyses in R

Abstract Summary After more than fifteen years of existence, the R package ape has continuously grown its contents, and has been used by a growing community of users. The releas...

Comprehensive molecular characterization of human colon and rectal cancer

Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

We describe a new basis for the construction of a genetic linkage map of the human genome. The basic principle of the mapping scheme is to develop, by recombinant DNA techniques...

Finding the missing heritability of complex diseases

Interorganizational Collaboration and the Locus of Innovation: Networks of Learning in Biotechnology

This research was supported by grants provided to the first author by the Social and Behavioral Sciences Research Institute, University of Arizona, and the Aspen Institute Nonpr...

<tt>BLAT</tt>—The <tt>BLAST</tt>-Like Alignment Tool

Analyzing vertebrate genomes requires rapid mRNA/DNA and cross-species protein alignments. A new tool, BLAT , is more accurate and 500 times faster than popular existing tools f...

Evaluation of general 16S ribosomal RNA gene PCR primers for classical and next-generation sequencing-based diversity studies

16S ribosomal RNA gene (rDNA) amplicon analysis remains the standard approach for the cultivation-independent investigation of microbial diversity. The accuracy of these analyse...