Publications
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Comparing the Standard EQ-5D Three-Level System with a Five-Level Version
The aim of this study is a head-to-head comparison of the performance of the three-level EQ-5D (3L) and a newly developed five-level version (5L). Eighty-two respondents valued ...
Measurement of Health Status in the 1990s
The use of health-related quality of life measures, especially those based on function, are likely to increase during the next decade. This increase, however, is most likely to ...
Life’s Simple 7 and Risk of Incident Stroke
Background and Purpose— The American Heart Association developed Life’s Simple 7 (LS7) as a metric defining cardiovascular health. We investigated the association between LS7 an...
Blood pressure from mid‐ to late life and risk of incident dementia
Elevated blood pressure during midlife, persistence of elevated blood pressure into late life, and, among nonhypertensives, a steep decline in blood pressure during mid- to late...
RAC Regulation of Actin Polymerization and Proliferation by a Pathway Distinct from Jun Kinase
The RAC guanine nucleotide binding proteins regulate multiple biological activities, including actin polymerization, activation of the Jun kinase (JNK) cascade, and cell prolife...
Detection of the human T cell lymphoma virus p19 in cells of some patients with cutaneous T cell lymphoma and leukemia using a monoclonal antibody.
A monoclonal antibody specific for the internal p19 protein of a type-C retrovirus (HTLV) isolated from human neoplastic T cells has been developed. Its specificity has been sho...
Psychometric properties of vision‐related quality of life questionnaires: a systematic review
Abstract The increased attention for quality of life (QOL) as an outcome measure has led to the development of numerous questionnaires to assess this construct in the field of o...
Life stress and health: Personality, coping, and family support in stress resistance.
The purpose of this study was to extend work on factors that buffer the potentially negative health effects of life stress. Using a survey with a representative community sample...
Psychometric Comparison of the Standard EQ-5D to a 5 Level Version in Cancer Patients
Evidence supported the validity of both EQ-5D-3L and EQ-5D-5L in cancer. However, results suggest a 5-level classifier system has less ceiling effect and greater discriminative ...
Causal Variables, Indicator Variables and Measurement Scales: An Example from Quality of Life
Summary There is extensive literature on the development and validation of multi-item measurement scales. Much of this is based on principles derived from psychometric theory an...