A scalable content-addressable network
Hash tables - which map "keys" onto "values" - are an essential building block in modern software systems. We believe a similar functionality would be equally valuable to large ...
Publications
Explore 892 academic publications
Showing 12 of
892 publications
The Astropy Project: Building an Open-science Project and Status of the v2.0 Core Package<sup>*</sup>
Abstract The Astropy Project supports and fosters the development of open-source and openly developed Python packages that provide commonly needed functionality to the astronomi...
Cancer immunotherapy using checkpoint blockade
The release of negative regulators of immune activation (immune checkpoints) that limit antitumor responses has resulted in unprecedented rates of long-lasting tumor responses i...
Interactive Tree Of Life (iTOL) v4: recent updates and new developments
Abstract The Interactive Tree Of Life (https://itol.embl.de) is an online tool for the display, manipulation and annotation of phylogenetic and other trees. It is freely availab...
Scaling Theory of Localization: Absence of Quantum Diffusion in Two Dimensions
Arguments are presented that the $T=0$ conductance $G$ of a disordered electronic system depends on its length scale $L$ in a universal manner. Asymptotic forms are obtained for...
Oxidants, antioxidants, and the degenerative diseases of aging.
Metabolism, like other aspects of life, involves tradeoffs. Oxidant by-products of normal metabolism cause extensive damage to DNA, protein, and lipid. We argue that this damage...
Improved side‐chain torsion potentials for the Amber ff99SB protein force field
Abstract Recent advances in hardware and software have enabled increasingly long molecular dynamics (MD) simulations of biomolecules, exposing certain limitations in the accurac...
The Immune Landscape of Cancer
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across cancer types, we identi...