Publications

The mutational constraint spectrum quantified from variation in 141,456 humans

Image Super-Resolution Using Deep Convolutional Networks

We propose a deep learning method for single image super-resolution (SR). Our method directly learns an end-to-end mapping between the low/high-resolution images. The mapping is...

Fast, sensitive and accurate integration of single-cell data with Harmony

Dating of the human-ape splitting by a molecular clock of mitochondrial DNA

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

Accurate structure prediction of biomolecular interactions with AlphaFold 3

Abstract The introduction of AlphaFold 2 1 has spurred a revolution in modelling the structure of proteins and their interactions, enabling a huge range of applications in prote...

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

Structural Holes

Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China

Older age was associated with greater risk of development of ARDS and death likely owing to less rigorous immune response. Although high fever was associated with the developmen...

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045

ape 5.0: an environment for modern phylogenetics and evolutionary analyses in R

Abstract Summary After more than fifteen years of existence, the R package ape has continuously grown its contents, and has been used by a growing community of users. The releas...