Publications
Explore 170 academic publications
Mendelian Randomization in the Era of Genomewide Association Studies
Abstract Background: Observational epidemiology has been instrumental in identifying modifiable causes of common diseases, and, in turn, substantially impacting public health. S...
Conformation-dependent phosphorylation of p53
Phosphorylation of the p53 tumor suppressor protein is known to modulate its functions. Using bacterially produced glutathione S -transferase (GST)-p53 fusion protein and baculo...
A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of <i>EGFR</i>
Abstract Background Malignant astrocytic gliomas in children show a remarkable biological and clinical diversity. Small in-frame insertions or missense mutations in the epiderma...
The five‐factor personality inventory: cross‐cultural generalizability across 13 countries
In the present study, we investigated the structural invariance of the Five‐Factor Personality Inventory (FFPI) across a variety of cultures. Self‐report data sets from ten Euro...
Concepts of epigenetics in prostate cancer development
Substantial evidence now supports the view that epigenetic changes have a role in the development of human prostate cancer. Analyses of the patterns of epigenetic alteration are...
Display of 3-D Digital Images: Computational Foundations and Medical Applications
These new approaches to 3-D medical imaging promise better and more cost-effective object identification, representation, and manipulation in space and time.