The Molecular Taxonomy of Primary Prostate Cancer
There is substantial heterogeneity among primary prostate cancers, evident in the spectrum of molecular abnormalities and its variable clinical course. As part of The Cancer Gen...
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1,055 publications
IDBA-UD: a <i>de novo</i> assembler for single-cell and metagenomic sequencing data with highly uneven depth
Abstract Motivation: Next-generation sequencing allows us to sequence reads from a microbial environment using single-cell sequencing or metagenomic sequencing technologies. How...
The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) — China, 2020
Background: An outbreak of 2019 novel coronavirus diseases in Wuhan, Hubei Province, China has spread quickly nationwide.Here, we report results of a descriptive, exploratory an...
The outbreak of COVID-19 coronavirus and its impact on global mental health
Background: The current outbreak of COVID-19 coronavirus infection among humans in Wuhan (China) and its spreading around the globe is heavily impacting on the global health and...
Toward discovery science of human brain function
Although it is being successfully implemented for exploration of the genome, discovery science has eluded the functional neuroimaging community. The core challenge remains the d...
PANTHER: A Library of Protein Families and Subfamilies Indexed by Function
In the genomic era, one of the fundamental goals is to characterize the function of proteins on a large scale. We describe a method, PANTHER, for relating protein sequence relat...
The effect of human mobility and control measures on the COVID-19 epidemic in China
Tracing infection from mobility data What sort of measures are required to contain the spread of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), which causes coron...
Thermodynamic Theory of Structure, Stability and Fluctuations
Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Per...
Understanding: the Drought Phenomenon: The Role of Definitions
The occurrence of widespread, severe drought in Africa, India, North America, China, the USSR, Australia, and western Europe has once again underscored the vulnerability of deve...
The complete sequence of a human genome
Since its initial release in 2000, the human reference genome has covered only the euchromatic fraction of the genome, leaving important heterochromatic regions unfinished. Addr...