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Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
The cBioPortal enables integration, visualization, and analysis of multidimensional cancer genomic and clinical data.
Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review
<b><i>Background:</i></b> Cancer immunotherapy, such as anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and anti-programmed death 1 (PD-1), has...
The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in Oncology
These results support the EORTC QLQ-C30 as a reliable and valid measure of the quality of life of cancer patients in multicultural clinical research settings. Work is ongoing to...
Parallel Distributed Processing
What makes people smarter than computers? These volumes by a pioneering neurocomputing group suggest that the answer lies in the massively parallel architecture of the human min...
Nearest neighbor pattern classification
The nearest neighbor decision rule assigns to an unclassified sample point the classification of the nearest of a set of previously classified points. This rule is independent o...
Tissue-based map of the human proteome
Protein expression across human tissues Sequencing the human genome gave new insights into human biology and disease. However, the ultimate goal is to understand the dynamic exp...
Self-efficacy mechanism in human agency.
This article addresses the centrality of the self-efficacy mechanism in human agency. Self-per- cepts of efficacy influence thought patterns, actions, and emotional arousal. In ...
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
Ipilimumab, with or without a gp100 peptide vaccine, as compared with gp100 alone, improved overall survival in patients with previously treated metastatic melanoma. Adverse eve...