UniProt: a worldwide hub of protein knowledge
The UniProt Knowledgebase is a collection of sequences and annotations for over 120 million proteins across all branches of life. Detailed annotations extracted from the literat...
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729 publications
Hallmarks of Cancer: New Dimensions
Abstract The hallmarks of cancer conceptualization is a heuristic tool for distilling the vast complexity of cancer phenotypes and genotypes into a provisional set of underlying...
Genome sequencing in microfabricated high-density picolitre reactors
The proliferation of large-scale DNA-sequencing projects in recent years has driven a search for alternative methods to reduce time and cost. Here we describe a scalable, highly...
Remdesivir for the Treatment of Covid-19 — Final Report
Our data show that remdesivir was superior to placebo in shortening the time to recovery in adults who were hospitalized with Covid-19 and had evidence of lower respiratory trac...
Molecular signatures database (MSigDB) 3.0
Abstract Motivation: Well-annotated gene sets representing the universe of the biological processes are critical for meaningful and insightful interpretation of large-scale geno...
Chemistry and Properties of Nanocrystals of Different Shapes
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemistry and Properties of Nanocrystals of Different ShapesClemens Burda, Xiaobo Chen, Radha Narayanan, and Mostafa A. El-SayedView ...
U1 snRNP regulates cancer cell migration and invasion in vitro
Abstract Stimulated cells and cancer cells have widespread shortening of mRNA 3’-untranslated regions (3’UTRs) and switches to shorter mRNA isoforms due to usage of more proxima...
Pfam: The protein families database in 2021
Abstract The Pfam database is a widely used resource for classifying protein sequences into families and domains. Since Pfam was last described in this journal, over 350 new fam...