Publications

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

Molecular portraits of human breast tumours

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

Ipilimumab, with or without a gp100 peptide vaccine, as compared with gp100 alone, improved overall survival in patients with previously treated metastatic melanoma. Adverse eve...

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

2013 ESH/ESC Guidelines for the management of arterial hypertension

The ESH/ESC Guidelines represent the views of the ESH and ESC and were arrived at after careful consideration of the available evidence at the time they were written.Health prof...

The Sequence of the Human Genome

A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp ...

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis

A method and server for predicting damaging missense mutations

SWISS-MODEL: homology modelling of protein structures and complexes

Homology modelling has matured into an important technique in structural biology, significantly contributing to narrowing the gap between known protein sequences and experimenta...

Bioconductor: open software development for computational biology and bioinformatics

A safe operating space for humanity