New Guidelines to Evaluate the Response to Treatment in Solid Tumors
Anticancer cytotoxic agents go through a process by which their antitumor activity-on the basis of the amount of tumor shrinkage they could generate-has been investigated. In th...
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1,434 publications
GENEPOP (Version 1.2): Population Genetics Software for Exact Tests and Ecumenicism
Journal Article GENEPOP (Version 1.2): Population Genetics Software for Exact Tests and Ecumenicism Get access M. Raymond, M. Raymond Institut des Sciences de l'Evolution, URA C...
The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in Oncology
These results support the EORTC QLQ-C30 as a reliable and valid measure of the quality of life of cancer patients in multicultural clinical research settings. Work is ongoing to...
Initial conditions and moment restrictions in dynamic panel data models
In this paper we consider estimation of the autoregressive error components model. When the autoregressive parameter is moderately large and the number of time series observatio...
Harmonizing the Metabolic Syndrome
A cluster of risk factors for cardiovascular disease and type 2 diabetes mellitus, which occur together more often than by chance alone, have become known as the metabolic syndr...
PhysioBank, PhysioToolkit, and PhysioNet
Abstract —The newly inaugurated Research Resource for Complex Physiologic Signals, which was created under the auspices of the National Center for Research Resources of the Nati...
Cancer statistics, 2014
Abstract Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths that will occur in the United States in the current year and compiles the mo...
Planetary boundaries: Guiding human development on a changing planet
Crossing the boundaries in global sustainability The planetary boundary (PB) concept, introduced in 2009, aimed to define the environmental limits within which humanity can safe...
Diagnosis and Management of the Metabolic Syndrome
The metabolic syndrome has received increased attention in the past few years. This statement from the American Heart Association (AHA) and the National Heart, Lung, and Blood I...
Tissue Plasminogen Activator for Acute Ischemic Stroke
Thrombolytic therapy for acute ischemic stroke has been approached cautiously because there were high rates of intracerebral hemorrhage in early clinical trials. We performed a ...
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
In this paper we report exploratory analyses of high-density oligonucleotide array data from the Affymetrix GeneChip system with the objective of improving upon currently used m...
Applied Longitudinal Data Analysis
Abstract Change is constant in everyday life. Infants crawl and then walk, children learn to read and write, teenagers mature in myriad ways, and the elderly become frail and fo...