Yishen Qianggu Mixture formulation suppresses osteometabolic inflammation by modulating the IL-17/NF-κB/MAPK signaling axis

Jun Zhao; Guang Peng; D. X. Xiao; Changbo Fu; Haozhu Chen; Shi‐Wei Luo; Han-Qing Wu; Mi Huang

doi:10.1016/j.jep.2025.121011

Abstract

YSQGM ameliorates bone metabolic imbalance in PMOP by suppressing proinflammatory mediators in the IL-17/NF-κB/MAPK signaling axis, providing novel mechanistic evidence for the use of TCM in PMOP prevention and treatment.

Keywords

Inflammatory responseIsoliquiritigenin (ISL)Postmenopausal osteoporosis (PMOP)Untargeted metabolomicsYishen Qianggu Mixture (YSQGM)

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Publication Info

Year: 2025
Type: article
Volume: 358
Pages: 121011-121011
Citations: 0
Access: Closed

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APA Style

                            
                                    Jun Zhao, 
                                
                                    Guang Peng, 
                                
                                    D. X. Xiao
                                
                                et al.
                            
                            (2025). 
                            Yishen Qianggu Mixture formulation suppresses osteometabolic inflammation by modulating the IL-17/NF-κB/MAPK signaling axis. 
                            Journal of Ethnopharmacology
                            , 358
                            
                            , 121011-121011.
                            https://doi.org/10.1016/j.jep.2025.121011

Identifiers

DOI: 10.1016/j.jep.2025.121011
PMID: 41386308

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Data completeness: 81%