Users' Guides to the Medical Literature

Abstract

<h3>CLINICAL SCENARIO</h3> A 55-year-old man had his serum cholesterol level measured at a shopping mall 2 months ago. His cholesterol level was elevated and he comes to you, his primary care physician, for advice. He does not smoke, is not obese, and does not have hypertension, diabetes mellitus, or any first-order relatives with premature coronary heart disease (CHD). You repeat his cholesterol test and schedule a follow-up appointment. The test confirms an elevated cholesterol level (7.9 mmol/L [305 mg/dL]), but before deciding on a treatment recommendation, you elect to find out just how big a reduction in the risk of CHD this patient could expect from a cholesterollowering diet or drug therapy. <h3>THE SEARCH</h3> There are a number of cholesterol-lowering trials, and instead of trying to find and review all of the original studies yourself, you use Grateful Med to find a recent overview. On the first subject line you

Keywords

MedicineCholesterolCoronary heart diseaseDiabetes mellitusBlood cholesterolTest (biology)Primary careScheduleDiseaseLdl cholesterolInternal medicineFamily medicineEndocrinology

Affiliated Institutions

McMaster University CA

Related Publications

The association of glycemia and cause-specific mortality in a diabetic population

S. E. Moss

<h3>Background:</h3> The purpose of this study was to investigate the association of glycemia with cause-specific mortality in a diabetic population. <h3>Methods:</h3> The study...

1994 Archives of Internal Medicine 61 citations

Is Pulse Pressure Useful in Predicting Risk for Coronary Heart Disease?

Stanley S. Franklin , Shehzad Akbar Khan , Nathan D. Wong +2 more

Background —Current definitions of hypertension are based on levels of systolic blood pressure (SBP) and diastolic blood pressure (DBP), but not on pulse pressure (PP). We exami...

1999 Circulation 1734 citations

Does the Relation of Blood Pressure to Coronary Heart Disease Risk Change With Aging?

Stanley S. Franklin , Martin G. Larson , Shehzad Akbar Khan +4 more

Background —We examined the relative importance of diastolic (DBP), systolic (SBP) and pulse pressure (PP) as predictors of coronary heart disease (CHD) risk in different age gr...

2001 Circulation 1366 citations

Singular Integrals and Differentiability Properties of Functions.

Elias M. Stein

Singular integrals are among the most interesting and important objects of study in analysis, one of the three main branches of mathematics. They deal with real and complex numb...

1971 10398 citations

Heart Disease and Stroke Statistics—2021 Update

Salim S. Virani , Álvaro Alonso , Hugo J. Aparicio +36 more

Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stro...

2021 Circulation 5362 citations

Publication Info

Year: 1994
Type: article
Volume: 272
Issue: 17
Pages: 1367-1367
Citations: 772
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Users' Guides to the Medical Literature

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

772

OpenAlex

Cite This

APA Style

                            
                                    Andrew D Oxman
                                
                            (1994). 
                            Users' Guides to the Medical Literature. 
                            JAMA
                            , 272
                            (17)
                            , 1367-1367.
                            https://doi.org/10.1001/jama.1994.03520170077040

Identifiers

DOI: 10.1001/jama.1994.03520170077040