Abstract
The presence of MSI defines a subset of colorectal carcinomas with special molecular etiology and characteristic clinical, pathologic features, inclusive of increased survival. The authors conclude that quantification of TILs may provide a simple, single criterion for choosing which colorectal carcinomas are candidates for MSI testing.
Keywords
Microsatellite instabilityTumor-infiltrating lymphocytesColorectal cancerMedicineDNA mismatch repairPathologyCarcinomaOncologyRectumPopulationMicrosatelliteInternal medicineCancer researchCancerBiologyImmunotherapyGenetics
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Publication Info
- Year
- 2001
- Type
- article
- Volume
- 91
- Issue
- 12
- Pages
- 2417-2422
- Citations
- 505
- Access
- Closed
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Cite This
Thomas C. Smyrk,
Patrice Watson,
Karen L. Kaul
et al.
(2001).
Tumor-infiltrating lymphocytes are a marker for microsatellite instability in colorectal carcinoma.
Cancer
, 91
(12)
, 2417-2422.
https://doi.org/10.1002/1097-0142(20010615)91:12<2417::aid-cncr1276>3.0.co;2-u
Identifiers
- DOI
- 10.1002/1097-0142(20010615)91:12<2417::aid-cncr1276>3.0.co;2-u