Therapeutic peptides: current applications and future directions

Abstract

Peptide drug development has made great progress in the last decade thanks to new production, modification, and analytic technologies. Peptides have been produced and modified using both chemical and biological methods, together with novel design and delivery strategies, which have helped to overcome the inherent drawbacks of peptides and have allowed the continued advancement of this field. A wide variety of natural and modified peptides have been obtained and studied, covering multiple therapeutic areas. This review summarizes the efforts and achievements in peptide drug discovery, production, and modification, and their current applications. We also discuss the value and challenges associated with future developments in therapeutic peptides.

Keywords

Drug discoveryBiochemical engineeringDrug deliveryNanotechnologyComputer scienceComputational biologyData scienceEngineeringBioinformaticsBiologyMaterials science

MeSH Terms

Drug DiscoveryPeptides

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Publication Info

Year: 2022
Type: review
Volume: 7
Issue: 1
Pages: 48-48
Citations: 1655
Access: Closed

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APA Style

                            
                                
                                    Lei Wang, 
                                
                                    Nanxi Wang, 
                                
                                    Wenping Zhang
                                
                                et al.
                            
                            (2022). 
                            Therapeutic peptides: current applications and future directions. 
                            Signal Transduction and Targeted Therapy
                            , 7
                            (1)
                            , 48-48.
                            https://doi.org/10.1038/s41392-022-00904-4
                        

Identifiers

DOI: 10.1038/s41392-022-00904-4
PMID: 35165272
PMCID: PMC8844085

Data Quality

Data completeness: 90%