The Relation of Virologic and Immunologic Markers to Clinical Outcomes after Nucleoside Therapy in HIV-Infected Adults with 200 to 500 CD4 Cells per Cubic Millimeter

1996 New England Journal of Medicine 483 citations

Abstract

Both the risk of the progression of HIV disease and the efficacy of antiretroviral therapy are strongly associated with the plasma level of HIV RNA and with the viral phenotype. The changes in the plasma concentration of HIV RNA predict the changes in CD4 cell counts and survival after treatment with reverse-transcriptase inhibitors.

Keywords

MedicineAntiretroviral therapyHuman immunodeficiency virus (HIV)ImmunologyVirologyNucleosideViral loadBiologyGenetics

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Publication Info

Year
1996
Type
article
Volume
335
Issue
15
Pages
1091-1098
Citations
483
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Closed

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David Katzenstein, Scott M. Hammer, Michael D. Hughes et al. (1996). The Relation of Virologic and Immunologic Markers to Clinical Outcomes after Nucleoside Therapy in HIV-Infected Adults with 200 to 500 CD4 Cells per Cubic Millimeter. New England Journal of Medicine , 335 (15) , 1091-1098. https://doi.org/10.1056/nejm199610103351502

Identifiers

DOI
10.1056/nejm199610103351502