The pathogenesis of septic acute renal failure

Abstract

This review suggests that, on the evidence available, septic acute renal failure is more likely to be an immune or toxic state rather than simply a hemodynamic condition. The authors speculate that future insights into its pathogenesis might lead to a paradigm shift away from the concept of acute tubular necrosis, which has never been convincingly shown in sepsis, to that of acute tubular apoptosis.

Keywords

MedicineSeptic shockSepsisAcute kidney injuryIntensive care medicineAcute tubular necrosisPathogenesisRhabdomyolysisOrgan dysfunctionShock (circulatory)Renal replacement therapyDiseaseKidneyInternal medicine

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Publication Info

Year: 2003
Type: review
Volume: 9
Issue: 6
Pages: 496-502
Citations: 191
Access: Closed

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APA Style

                            
                                
                                    Li Wan, 
                                
                                    Rinaldo Bellomo, 
                                
                                    David Di Giantomasso
                                
                                et al.
                            
                            (2003). 
                            The pathogenesis of septic acute renal failure. 
                            Current Opinion in Critical Care
                            , 9
                            (6)
                            , 496-502.
                            https://doi.org/10.1097/00075198-200312000-00006
                        

Identifiers

DOI: 10.1097/00075198-200312000-00006