Abstract

Part 1 General approaches to the analysis of complex synthetic problems: the basis for retrosynthetic analysis transform-based strategies structure-based and topological strategies stereochemical strategies functional group-based and other strategies concurrent use of several strategies. Part 2 Specific pathways for the synthesis of complex molecules: macrocyclic structures heterocyclic structures sesquiterprenoids polycyclic isoprenoids prostanoids leukotrienes and other bioactive polyenes. Part 3 Guide to the original literature of multistep synthesis.

Keywords

Retrosynthetic analysisChemistryCombinatorial chemistryStereochemistryTotal synthesis

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Year
2011
Type
book
Citations
578
Access
Closed

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E. J. Corey, Xue‐Min Cheng (2011). The Logic of Chemical Synthesis. Medical Entomology and Zoology .