Abstract

The Gene Ontology (GO) project (http://www.geneontology.org/) provides a set of structured, controlled vocabularies for community use in annotating genes, gene products and sequences (also see http://www.sequenceontology.org/). The ontologies have been extended and refined for several biological areas, and improvements to the structure of the ontologies have been implemented. To improve the quantity and quality of gene product annotations available from its public repository, the GO Consortium has launched a focused effort to provide comprehensive and detailed annotation of orthologous genes across a number of 'reference' genomes, including human and several key model organisms. Software developments include two releases of the ontology-editing tool OBO-Edit, and improvements to the AmiGO browser interface.

Keywords

AnnotationOntologyBiologyGene ontologyGene AnnotationGene nomenclatureSet (abstract data type)World Wide WebInterface (matter)SoftwareGenomeComputer scienceComputational biologyGeneInformation retrievalBioinformaticsGeneticsTaxonomy (biology)Ecology

MeSH Terms

AnimalsDatabasesGeneticGenomicsHumansInternetMiceRatsSequence AnalysisUser-Computer InterfaceVocabularyControlled

Related Publications

Publication Info

Year
2007
Type
article
Volume
36
Issue
suppl_1
Pages
D440-D444
Citations
761
Access
Closed

Social Impact

Altmetric

Social media, news, blog, policy document mentions

Citation Metrics

761
OpenAlex
20
Influential
630
CrossRef

Cite This

The Gene Ontology Consortium (2007). The Gene Ontology project in 2008. Nucleic Acids Research , 36 (suppl_1) , D440-D444. https://doi.org/10.1093/nar/gkm883

Identifiers

DOI
10.1093/nar/gkm883
PMID
17984083
PMCID
PMC2238979

Data Quality

Data completeness: 86%