Abstract

• Patients with Alzheimer's disease and multi-infarct dementia were studied with scans using fluorodeoxyglucose tagged with fluorine 18. The rates of glucose metabolism were calculated. Patients with Alzheimer's dementia showed decreased metabolism in all areas of the brain but with preferential sparing of the primary motor and sensory cortex. Patients with multi-infarct dementia also had global reductions in glucose metabolic rates when compared with normal control subjects, but the areas of hypometabolism were focal and asymmetric.

Keywords

DementiaFluorodeoxyglucoseMedicineAlzheimer's diseaseDiseaseCarbohydrate metabolismInternal medicinePositron emission tomographyCardiologyRadiology

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Year
1983
Type
article
Volume
40
Issue
12
Pages
711-714
Citations
391
Access
Closed

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D. Frank Benson, Dietmar Kuhl, R A Hawkins et al. (1983). The Fluorodeoxyglucose 18F Scan in Alzheimer's Disease and Multi-infarct Dementia. Archives of Neurology , 40 (12) , 711-714. https://doi.org/10.1001/archneur.1983.04050110029003

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DOI
10.1001/archneur.1983.04050110029003