The Effect of Vitamin E and Beta Carotene on the Incidence of Lung Cancer and Other Cancers in Male Smokers

1994 New England Journal of Medicine 4,688 citations

Abstract

We found no reduction in the incidence of lung cancer among male smokers after five to eight years of dietary supplementation with alpha-tocopherol or beta carotene. In fact, this trial raises the possibility that these supplements may actually have harmful as well as beneficial effects.

Keywords

MedicineLung cancerIncidence (geometry)Vitamin Ebeta-CaroteneConfidence intervalGastroenterologyCancerVitaminPlaceboInternal medicineTocopherolRelative riskPathologyBiologyAntioxidant

Related Publications

Publication Info

Year
1994
Type
article
Volume
330
Issue
15
Pages
1029-1035
Citations
4688
Access
Closed

External Links

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

4688
OpenAlex

Cite This

(1994). The Effect of Vitamin E and Beta Carotene on the Incidence of Lung Cancer and Other Cancers in Male Smokers. New England Journal of Medicine , 330 (15) , 1029-1035. https://doi.org/10.1056/nejm199404143301501

Identifiers

DOI
10.1056/nejm199404143301501