Abstract
Digoxin did not reduce overall mortality, but it reduced the rate of hospitalization both overall and for worsening heart failure. These findings define more precisely the role of digoxin in the management of chronic heart failure.
Keywords
DigoxinMedicineHeart failureEjection fractionPlaceboConfidence intervalInternal medicineSinus rhythmRelative riskRandomized controlled trialCardiologyAtrial fibrillation
MeSH Terms
AgedArrhythmiasCardiacCardiotonic AgentsCardiovascular DiseasesDigoxinDouble-Blind MethodFemaleHeart FailureHospitalizationHumansMaleMiddle AgedStroke VolumeTreatment Outcome
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Publication Info
- Year
- 1997
- Type
- article
- Volume
- 336
- Issue
- 8
- Pages
- 525-533
- Citations
- 2957
- Access
- Closed
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Cite This
The Digitalis Investigation Group
(1997).
The Effect of Digoxin on Mortality and Morbidity in Patients with Heart Failure.
New England Journal of Medicine
, 336
(8)
, 525-533.
https://doi.org/10.1056/nejm199702203360801
Identifiers
- DOI
- 10.1056/nejm199702203360801
- PMID
- 9036306