Keywords

BiologySUMO proteinDNA damageDNA repairCell biologyUbiquitinDNAAcetylationComputational biologySignal transductionPhosphorylationPosttranslational modificationGeneticsBiochemistryGene

Affiliated Institutions

Related Publications

Regulation ofp53downstream genes

The p53 tumor suppressor is the most commonly mutated gene in human cancer. p53 protein is stabilized in response to different checkpoints activated by DNA damage, hypoxia, vira...

1998 Seminars in Cancer Biology 783 citations

Publication Info

Year
2007
Type
review
Volume
18
Issue
1
Pages
8-16
Citations
223
Access
Closed

External Links

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

223
OpenAlex

Cite This

Michael S.Y. Huen, Junjie Chen (2007). The DNA damage response pathways: at the crossroad of protein modifications. Cell Research , 18 (1) , 8-16. https://doi.org/10.1038/cr.2007.109

Identifiers

DOI
10.1038/cr.2007.109