Abstract

Summary The principles of linkage detection and measurement are traced from the first discovery of linkage to its present‐day use in human genetics. Some indications are given of their success and of the present problems and challenges facing them.

Keywords

Linkage (software)Genetic linkageGeneticsBiologyComputational biologyData scienceComputer scienceGene

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Publication Info

Year
1986
Type
review
Volume
50
Issue
4
Pages
293-311
Citations
15
Access
Closed

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Cedric A. B. Smith (1986). The development of human linkage analysis. Annals of Human Genetics , 50 (4) , 293-311. https://doi.org/10.1111/j.1469-1809.1986.tb01752.x

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DOI
10.1111/j.1469-1809.1986.tb01752.x