The Design and Analysis of Clinical Experiments

Joseph L. Fleiss

doi:10.1002/9781118032923

Abstract

Reliability of Measurement. Simple Linear Regression Analysis. The Parallel Groups Design. Special Cases of the Parallel Groups Study. Blocking to Control for Prognostic Variables. Stratification to Control for Prognostic Variables. Analysis of Covariance and the Study of Change. Repeated Measurements Studies. Latin and Greco-Latin Squares. The Crossover Study. Balanced Incomplete Block Designs. Factorial Experiments. Split-Plot Designs and Confounding. Appendix. Indexes.

Keywords

StatisticsConfoundingAnalysis of covarianceMathematicsCovarianceBlock designLatin squareEconometricsCrossoverComputer scienceArtificial intelligenceCombinatorics

Related Publications

Experimental Design: Procedures for the Behavioral Sciences

Roger E. Kirk

Chapter 1. Research Strategies and the Control of Nuisance Variables Chapter 2. Experimental Designs: an Overview Chapter 3. Fundamental Assumptions in Analysis of Variance Chap...

2013 8576 citations

Statistical principles in experimental design.

B. J. WINER

CHAPTER 1: Introduction to Design CHAPTER 2: Principles of Estimation and Inference: Means and Variance CHAPTER 3: Design and Analysis of Single-Factor Experiments: Completely R...

1962 McGraw-Hill Book Company 26927 citations

Quality by Experimental Design.

John Disney , Tim Barker

THE PHILOSOPHY OF EXPERIMENTATION Why Design Experiments? Organizing the Experiment The Neglected Response Variable STATISTICAL EXPERIMENTAL DESIGN The Factorial 2-Level Design ...

1996 Journal of the Royal Statistical Soci... 210 citations

Statistical design and analysis of experiments: with applications to engineering and science

Bruce L. Bowerman

Preface. PART I: FUNDAMENTAL STATISTICAL CONCEPTS. Statistics in Engineering and Science. Fundamentals of Statistical Inference. Inferences on Means and Standard Deviations. PAR...

1990 Choice Reviews Online 957 citations

Experimental Design and Data Analysis for Biologists

Gerry P. Quinn , Michael J. Keough

An essential textbook for any student or researcher in biology needing to design experiments, sample programs or analyse the resulting data. The text begins with a revision of e...

2002 Cambridge University Press eBooks 10558 citations

Publication Info

Year: 1999
Type: book
Citations: 4314
Access: Closed

External Links

Download PDF (Free) View on DOI.org Semantic Scholar

Social Impact

Altmetric

The Design and Analysis of Clinical Experiments

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

4314

OpenAlex

Influential

361

CrossRef

Cite This

APA Style

                            
                                    Joseph L. Fleiss
                                
                            (1999). 
                            The Design and Analysis of Clinical Experiments. 
                            
                            .
                            https://doi.org/10.1002/9781118032923

Identifiers

DOI: 10.1002/9781118032923

Data Quality

Data completeness: 70%