The contemporary spectrum of multiple sclerosis misdiagnosis

Andrew Solomon; Dennis Bourdette; Anne H. Cross; Angela Applebee; Philip Skidd; Diantha B. Howard; Rebecca Spain; Michelle Cameron; Edward Kim; Michele Mass; Vijayshree Yadav; Ruth H. Whitham; Erin E. Longbrake; Robert T. Naismith; Gregory F. Wu; Becky Parks; Dean M. Wingerchuk; Brian Rabin; Michel Toledano; W. Oliver Tobin; Orhun H. Kantarci; Jonathan L. Carter; B. Mark Keegan; Brian G. Weinshenker

doi:10.1212/wnl.0000000000003152

Abstract

Misdiagnosis of MS leads to unnecessary and potentially harmful risks to patients. Misinterpretation and misapplication of MS clinical and radiographic diagnostic criteria are important contemporary contributors to misdiagnosis.

Keywords

Neuromyelitis opticaMedicineMultiple sclerosisMedical diagnosisPsychogenic diseaseSpectrum disorderPediatricsDiseaseFibromyalgiaMigraineDemyelinating DisorderDemyelinating diseaseDermatologyPhysical therapyRadiologyPsychiatryPathology

Affiliated Institutions

Related Publications

Diagnosis of multiple sclerosis: progress and challenges

Wallace Brownlee , Todd A. Hardy , Franz Fazekas +1 more

2016 The Lancet 645 citations

Evaluation of McDonald MRI criteria for dissemination in space in Korean patients with clinically isolated syndromes

So‐Young Huh , Su‐Hyun Kim , Woojun Kim +6 more

We investigated the validity of the 2005 and 2010 McDonald magnetic resonance imaging (MRI) criteria for dissemination in space (DIS) to predict the conversion of clinically def...

2013 Multiple Sclerosis Journal 14 citations

The clinical course of neuromyelitis optica (Devic’s syndrome)

Dean M. Wingerchuk , William F. Hogancamp , Peter C. O’Brien +1 more

Clinical, laboratory, and imaging features generally distinguish neuromyelitis optica from MS. Patients with relapsing optic neuritis and myelitis may have neuromyelitis optica ...

1999 Neurology 1788 citations

Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica

Norio Chihara , Toshimasa Aranami , Wakiro Sato +6 more

Neuromyelitis optica (NMO) is an inflammatory disease affecting the optic nerve and spinal cord, in which autoantibodies against aquaporin 4 (AQP4) water channel protein probabl...

2011 Proceedings of the National Academy o... 456 citations

Clinical improvement in a patient with neuromyelitis optica following therapy with the anti-IL-6 receptor monoclonal antibody tocilizumab

M. Araki , Toshimasa Aranami , Takako Matsuoka +3 more

Neuromyelitis optica (NMO) is a disabling autoimmune disease associated with an elevation of anti-aquaporin 4 (AQP4) autoantibodies. Here, we present a case with NMO who respond...

2012 Modern Rheumatology 104 citations

Publication Info

Year: 2016
Type: article
Volume: 87
Issue: 13
Pages: 1393-1399
Citations: 305
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

The contemporary spectrum of multiple sclerosis misdiagnosis

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

305

OpenAlex

Cite This

APA Style

                            
                                
                                    Andrew Solomon, 
                                
                                    Dennis Bourdette, 
                                
                                    Anne H. Cross
                                
                                et al.
                            
                            (2016). 
                            The contemporary spectrum of multiple sclerosis misdiagnosis. 
                            Neurology
                            , 87
                            (13)
                            , 1393-1399.
                            https://doi.org/10.1212/wnl.0000000000003152
                        

Identifiers

DOI: 10.1212/wnl.0000000000003152