Abstract

We created an accurate independent estimate for 28-day mortality risk for patients with sepsis syndrome (severe sepsis). This estimate could improve the evaluation of new drugs by investigating whether the drug's benefit varies by patient risk and then determining the amount of benefit for individual patients.

Keywords

MedicineSepsisIntensive care unitReceiver operating characteristicSystemic inflammatory response syndromeIntensive care medicineIntensive careRetrospective cohort studyEmergency medicineInternal medicine

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Publication Info

Year
1993
Type
article
Volume
270
Issue
10
Pages
1233-1233
Citations
199
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Closed

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199
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Cite This

William A. Knaus (1993). The Clinical Evaluation of New Drugs for Sepsis. JAMA , 270 (10) , 1233-1233. https://doi.org/10.1001/jama.1993.03510100083038

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DOI
10.1001/jama.1993.03510100083038