Abstract

A randomized trial was conducted at the Institut Gustave-Roussy (IGR) between 1972 and 1980 comparing tumorectomy and breast irradiation with modified radical mastectomy. One hundred and seventy-nine patients with an infiltrating breast carcinoma up to 20 mm in diameter at macroscopic examination were included: 88 had conservative management, and 91 a mastectomy. All patients had a low-axillary dissection with immediate histological examination. For the patients with positive axillary nodes, a complete axillary dissection was undertaken. Overall survival, distant metastasis, contralateral breast cancer and locoregional recurrence rates were not significantly different between the two treatment groups.

Keywords

MedicineAxillary DissectionBreast cancerMastectomyRandomized controlled trialSurgeryModified Radical MastectomyTotal MastectomyRadical mastectomyConservative treatmentDissection (medical)Distant metastasisMetastasisCancerInternal medicine

MeSH Terms

AdenocarcinomaAdultAgedBreast NeoplasmsClinical Trials as TopicCombined Modality TherapyFemaleFollow-Up StudiesHumansMastectomyModified RadicalMastectomySegmentalMiddle AgedNeoplasm RecurrenceLocalRandom Allocation

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Publication Info

Year
1989
Type
article
Volume
14
Issue
3
Pages
177-184
Citations
566
Access
Closed

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Cite This

D Sarrazin, Monique G. Lê, R. Arriagada et al. (1989). Ten-year results of a randomized trial comparing a conservative treatment to mastectomy in early breast cancer. Radiotherapy and Oncology , 14 (3) , 177-184. https://doi.org/10.1016/0167-8140(89)90165-5

Identifiers

DOI
10.1016/0167-8140(89)90165-5
PMID
2652199

Data Quality

Data completeness: 81%