Abstract

Improved understanding of the biology and molecular subtypes of non-small cell lung cancer have led to more biomarker-directed therapies for patients with metastatic disease. These biomarker-directed therapies and newer empirical treatment regimens have improved overall survival for patients with metastatic non-small cell lung cancer.

Keywords

MedicineCrizotinibLung cancerGefitinibPemetrexedErlotinibCarboplatinROS1Targeted therapyCancer researchOncologyAnaplastic lymphoma kinaseAfatinibCancerInternal medicineChemotherapyEpidermal growth factor receptorAdenocarcinomaCisplatin

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Publication Info

Year
2019
Type
review
Volume
322
Issue
8
Pages
764-764
Citations
1045
Access
Closed

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Cite This

Kathryn C. Arbour, Gregory J. Riely (2019). Systemic Therapy for Locally Advanced and Metastatic Non–Small Cell Lung Cancer. JAMA , 322 (8) , 764-764. https://doi.org/10.1001/jama.2019.11058

Identifiers

DOI
10.1001/jama.2019.11058