Systematic Transcriptome Wide Analysis of lncRNA-miRNA Interactions

Saakshi Jalali; Deeksha Bhartiya; Mukesh Kumar Lalwani; Sridhar Sivasubbu; Vinod Scaria

doi:10.1371/journal.pone.0053823

Abstract

This analysis suggests widespread regulatory interactions between noncoding RNAs classes and suggests a novel functional role for lncRNAs. We also present the first transcriptome scale study on miRNA-lncRNA interactions and the first report of a genome-scale reconstruction of a noncoding RNA regulatory interactome involving lncRNAs.

Keywords

BiologyTranscriptomeLong non-coding RNAComputational biologymicroRNANon-coding RNAGenomeArgonauteSmall nucleolar RNARNAGeneticsGeneGene expressionRNA interference

MeSH Terms

AnimalsBase SequenceBinding SitesGene Expression ProfilingGenomeHumansMicroRNAsMolecular Sequence DataRNALong NoncodingRNAMessengerTranscriptomeZebrafish

Affiliated Institutions

Institute of Genomics and Integrative Biology IN

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Publication Info

Year: 2013
Type: article
Volume: 8
Issue: 2
Pages: e53823-e53823
Citations: 426
Access: Closed

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APA Style

                            
                                
                                    Saakshi Jalali, 
                                
                                    Deeksha Bhartiya, 
                                
                                    Mukesh Kumar Lalwani
                                
                                et al.
                            
                            (2013). 
                            Systematic Transcriptome Wide Analysis of lncRNA-miRNA Interactions. 
                            PLoS ONE
                            , 8
                            (2)
                            , e53823-e53823.
                            https://doi.org/10.1371/journal.pone.0053823
                        

Identifiers

DOI: 10.1371/journal.pone.0053823
PMID: 23405074
PMCID: PMC3566149
arXiv: 1208.0154

Data Quality

Data completeness: 88%