Keywords
BiologyGolgi apparatusProtein targetingCell biologyGlycolipidMembrane proteinVesicleTransport proteinEpithelial polarityBiochemistrySphingolipidIntracellularCell membraneMembraneApical membraneEndoplasmic reticulum
Affiliated Institutions
Related Publications
Traffic, polarity, and detergent solubility of a glycosylphosphatidylinositol-anchored protein after LDL-deprivation of MDCK cells.
Glycosylphosphatidylinositol-anchored proteins, GPI-proteins, are selectively delivered to the apical surfaces of many types of morphologically polarized epithelial cells. It ha...
Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells
GPI-linked protein molecules become Triton-insoluble during polarized sorting to the apical cell surface of epithelial cells. These insoluble complexes, enriched in cholesterol,...
Involvement of Detergent-Insoluble Complexes in the Intracellular Transport of Intestinal Brush Border Enzymes
A number of transmembrane digestive enzymes of the porcine small intestinal brush border membrane were found to be partially Triton X-100-insoluble at 0 degree C and colocalized...
Polarized apical distribution of glycosyl-phosphatidylinositol-anchored proteins in a renal epithelial cell line.
Polarized epithelial cell monolayers contain two distinct plasma membrane domains as delineated by the presence of tight junctions--i.e., an apical surface that faces the extern...
Detergent-insoluble glycolipid microdomains in lymphocytes in the absence of caveolae.
Antibody binding to glycolipids and glycophosphatidylinositol (GPI)-anchored proteins of lymphocytes can trigger activation of specific signal transduction pathways. The finding...
Publication Info
- Year
- 1992
- Type
- article
- Volume
- 68
- Issue
- 3
- Pages
- 533-544
- Citations
- 2901
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
2901
OpenAlex
Cite This
Deborah A. Brown,
John K. Rose
(1992).
Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface.
Cell
, 68
(3)
, 533-544.
https://doi.org/10.1016/0092-8674(92)90189-j
Identifiers
- DOI
- 10.1016/0092-8674(92)90189-j