Abstract

The presence of microparticles of clay is demonstrated in the dermis of the foot in a patient with endemic elephantiasis. The particles are seen to be in the phagosomes of macrophages or in the cytoplasm of other cells. The conducting lymphatic in the subdermal tissue is found to be impermeable to Patent Blue Violet dye and to be fibrosed. The failure to conduct lymph to the node produces a permanent deposit of silica in the dermal tissues; a parallel is drawn with similar deposits in the lung in pneumoconiosis.

Keywords

ElephantiasisLymphatic systemDermisLymphedemaPathologyLymph nodeFoot (prosody)LymphAnatomyMedicineBiologyImmunologyFilariasisHelminthsInternal medicine

MeSH Terms

AdultElectron Probe MicroanalysisElephantiasisFemaleFootHumansLymphedemaMacrophagesMicroscopyElectronSkinSoil

Affiliated Institutions

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Publication Info

Year
1989
Type
article
Volume
83
Issue
4
Pages
381-385
Citations
56
Access
Closed

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56
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5
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Cite This

Gillian Blundell, W. J. Henderson, E. W. Price (1989). Soil particles in the tissues of the foot in endemic elephantiasis of the lower legs. Annals of Tropical Medicine and Parasitology , 83 (4) , 381-385. https://doi.org/10.1080/00034983.1989.11812361

Identifiers

DOI
10.1080/00034983.1989.11812361
PMID
2604475

Data Quality

Data completeness: 81%