Abstract
Individual carbocyanine dye molecules in a sub-monolayer spread have been imaged with near-field scanning optical microscopy. Molecules can be repeatedly detected and spatially localized (to ∼λ/50 where λ is the wavelength of light) with a sensitivity of at least 0.005 molecules/(Hz) 1/2 and the orientation of each molecular dipole can be determined. This information is exploited to map the electric field distribution in the near-field aperture with molecular spatial resolution.
Keywords
MicroscopyOptical microscopeMoleculeMonolayerLambdaDipoleResolution (logic)WavelengthOpticsNear-field scanning optical microscopeAperture (computer memory)Field (mathematics)Electric fieldMaterials scienceMolecular physicsChemistryPhysicsNanotechnologyScanning electron microscope
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Publication Info
- Year
- 1993
- Type
- article
- Volume
- 262
- Issue
- 5138
- Pages
- 1422-1425
- Citations
- 1245
- Access
- Closed
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Cite This
Eric Betzig,
Robert J. Chichester
(1993).
Single Molecules Observed by Near-Field Scanning Optical Microscopy.
Science
, 262
(5138)
, 1422-1425.
https://doi.org/10.1126/science.262.5138.1422
Identifiers
- DOI
- 10.1126/science.262.5138.1422