SETBP1 mutations occur in 9% of MDS/MPN and in 4% of MPN cases and are strongly associated with atypical CML, monosomy 7, isochromosome i(17)(q10),...

Keywords

IsochromosomeMyeloidMyelofibrosisMyelodysplastic syndromesBiologyImmunologyBone marrowGeneticsGene

Affiliated Institutions

Related Publications

An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms

Tariq I. Mughal , Nicholas C.P. Cross , E. Padron +15 more

In the 2008 WHO classification, chronic myeloid malignancies that share both myelodysplastic and myeloproliferative features define the myelodysplastic/myeloproliferative group,...

2015 Haematologica 98 citations

Prognostic Score Including Gene Mutations in Chronic Myelomonocytic Leukemia

Raphaël Itzykson , Olivier Kosmider , Aline Renneville +20 more

Purpose Several prognostic scoring systems have been proposed for chronic myelomonocytic leukemia (CMML), a disease in which some gene mutations—including ASXL1—have been associ...

2013 Journal of Clinical Oncology 535 citations

Oncogenic<i>CSF3R</i>Mutations in Chronic Neutrophilic Leukemia and Atypical CML

Julia E. Maxson , Jason Gotlib , Daniel A. Pollyea +16 more

Mutations in CSF3R are common in patients with CNL or atypical CML and represent a potentially useful criterion for diagnosing these neoplasms. (Funded by the Leukemia and Lymph...

2013 New England Journal of Medicine 555 citations

The myelodysplastic/myeloproliferative neoplasms: myeloproliferative diseases with dysplastic features

Attilio Orazi , Ulrich Germing

2008 Leukemia 184 citations

Efficacy of ruxolitinib in myeloid neoplasms with PCM1-JAK2 fusion gene

Elisa Rumi , Jelena D. Milosevic Feenstra , Dominik Selleslag +11 more

2015 Annals of Hematology 59 citations

Publication Info

Year: 2013
Type: article
Volume: 27
Issue: 9
Pages: 1852-1860
Citations: 186
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

SETBP1 mutations occur in 9% of MDS/MPN and in 4% of MPN cases and are strongly associated with atypical CML, monosomy 7, isochromosome i(17)(q10), ASXL1 and CBL mutations

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

186

OpenAlex

Cite This

APA Style

                            
                                
                                    Manja Meggendorfer, 
                                
                                    Ulrike Bacher, 
                                
                                    Tamara Alpermann
                                
                                et al.
                            
                            (2013). 
                            SETBP1 mutations occur in 9% of MDS/MPN and in 4% of MPN cases and are strongly associated with atypical CML, monosomy 7, isochromosome i(17)(q10), ASXL1 and CBL mutations. 
                            Leukemia
                            , 27
                            (9)
                            , 1852-1860.
                            https://doi.org/10.1038/leu.2013.133
                        

Identifiers

DOI: 10.1038/leu.2013.133