Semiconductor Nanocrystals as Fluorescent Biological Labels

Abstract

Semiconductor nanocrystals were prepared for use as fluorescent probes in biological staining and diagnostics. Compared with conventional fluorophores, the nanocrystals have a narrow, tunable, symmetric emission spectrum and are photochemically stable. The advantages of the broad, continuous excitation spectrum were demonstrated in a dual-emission, single-excitation labeling experiment on mouse fibroblasts. These nanocrystal probes are thus complementary and in some cases may be superior to existing fluorophores.

Keywords

NanocrystalFluorescenceSemiconductorMaterials scienceOptoelectronicsExcitationBroad spectrumNanotechnologyChemistryOpticsPhysics

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Publication Info

Year: 1998
Type: article
Volume: 281
Issue: 5385
Pages: 2013-2016
Citations: 8529
Access: Closed

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APA Style

                            
                                
                                    Marcel P. Bruchez, 
                                
                                    Mario M. Moronne, 
                                
                                    Peter Gin
                                
                                et al.
                            
                            (1998). 
                            Semiconductor Nanocrystals as Fluorescent Biological Labels. 
                            Science
                            , 281
                            (5385)
                            , 2013-2016.
                            https://doi.org/10.1126/science.281.5385.2013
                        

Identifiers

DOI: 10.1126/science.281.5385.2013