Abstract

Despite evidence of heterogeneity across studies, these meta-analytic results from 12 published twin studies of schizophrenia are consistent with a view of schizophrenia as a complex trait that results from genetic and environmental etiological influences. These results are broadly informative in that they provide no information about the specific identity of these etiological influences, but they do provide a component of a unifying empirical basis supporting the rationality of searches for underlying genetic and common environmental etiological factors.

Keywords

Schizophrenia (object-oriented programming)Twin studyMeta-analysisHeritabilityTraitEtiologyPsychologyClinical psychologyConfidence intervalPsychiatryMedicineGeneticsBiologyInternal medicineComputer science

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1990 International Review of Psychiatry 202 citations

Publication Info

Year
2003
Type
review
Volume
60
Issue
12
Pages
1187-1187
Citations
2322
Access
Closed

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Patrick F. Sullivan, Kenneth S. Kendler, Michael C. Neale (2003). Schizophrenia as a Complex Trait. Archives of General Psychiatry , 60 (12) , 1187-1187. https://doi.org/10.1001/archpsyc.60.12.1187

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DOI
10.1001/archpsyc.60.12.1187