Abstract

TO THE EDITOR:
\nAs of March 10, 2020, the 2019 novel coronavirus (SARS-CoV-2) has been responsible for more than 110,000 infections and 4000 deaths worldwide, but data regarding the epidemiologic characteristics and clinical features of infected children are limited.1-3 A recent review of 72,314 cases by the Chinese Center for Disease Control and Prevention showed that less than 1% of the cases were in children younger than 10 years of age.2 In order to determine the spectrum of disease in children, we evaluated children infected with SARS-CoV-2 and treated at the Wuhan Children’s Hospital, the only center assigned by the central government for treating infected children under 16 years of age in Wuhan. Both symptomatic and asymptomatic children with known contact with persons having confirmed or suspected SARS-CoV-2 infection were evaluated. Nasopharyngeal or throat swabs were obtained for detection of SARS-CoV-2 RNA by established methods.4 The clinical outcomes were monitored up to March 8, 2020.

Keywords

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Medicine2019-20 coronavirus outbreakPediatricsChinaVirologyOutbreakGeographyDiseaseInternal medicineInfectious disease (medical specialty)

MeSH Terms

AdolescentAge DistributionAsymptomatic DiseasesBetacoronavirusCOVID-19ChildChildPreschoolChinaComorbidityCoronavirus InfectionsCoughFemaleFeverHumansInfantLungMalePandemicsPatient AcuityPneumoniaViralSARS-CoV-2Sex Distribution

Related Publications

Publication Info

Year
2020
Type
article
Volume
382
Issue
17
Pages
1663-1665
Citations
2503
Access
Closed

External Links

Download PDF (Free) View on DOI.org PubMed Semantic Scholar

Social Impact

Altmetric
PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

2503
OpenAlex
123
Influential
1891
CrossRef

Cite This

Xiaoxia Lü, Liqiong Zhang, Hui Du et al. (2020). SARS-CoV-2 Infection in Children. New England Journal of Medicine , 382 (17) , 1663-1665. https://doi.org/10.1056/nejmc2005073

Identifiers

DOI
10.1056/nejmc2005073
PMID
32187458
PMCID
PMC7121177

Data Quality

Data completeness: 86%