Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Hip Arthroplasty

Abstract

A once-daily, 10-mg oral dose of rivaroxaban was significantly more effective for extended thromboprophylaxis than a once-daily, 40-mg subcutaneous dose of enoxaparin in patients undergoing elective total hip arthroplasty. The two drugs had similar safety profiles. (ClinicalTrials.gov number, NCT00329628.)

Keywords

MedicineRivaroxabanPulmonary embolismDeep veinSurgeryVenographyEnoxaparin sodiumThrombosisVenous thrombosisPlaceboAnesthesiaLow molecular weight heparinInternal medicineWarfarinAtrial fibrillation

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Publication Info

Year: 2008
Type: article
Volume: 358
Issue: 26
Pages: 2765-2775
Citations: 1419
Access: Closed

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APA Style

                            
                                
                                    Bengt I. Eriksson, 
                                
                                    Lars C. Borris, 
                                
                                    Richard J. Friedman
                                
                                et al.
                            
                            (2008). 
                            Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Hip Arthroplasty. 
                            New England Journal of Medicine
                            , 358
                            (26)
                            , 2765-2775.
                            https://doi.org/10.1056/nejmoa0800374
                        

Identifiers

DOI: 10.1056/nejmoa0800374