Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome

Abstract

By comparing the sequences of tumor and skin genomes of a patient with AML-M1, we have identified recurring mutations that may be relevant for pathogenesis.

Keywords

GenomeBiologyGeneticsNeuroblastoma RAS viral oncogene homologGeneMutationPoint mutationMyeloid leukemiaDNA sequencingCancer researchKRAS

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Publication Info

Year: 2009
Type: article
Volume: 361
Issue: 11
Pages: 1058-1066
Citations: 2196
Access: Closed

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APA Style

                            
                                
                                    Elaine R. Mardis, 
                                
                                    Li Ding, 
                                
                                    David J. Dooling
                                
                                et al.
                            
                            (2009). 
                            Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome. 
                            New England Journal of Medicine
                            , 361
                            (11)
                            , 1058-1066.
                            https://doi.org/10.1056/nejmoa0903840
                        

Identifiers

DOI: 10.1056/nejmoa0903840